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["附2：                          西安交大2004-2005年度获生命学部资助的项目清单"]
["序号","项目编号","项目名称","单位","负责人","起止年限","经费（万元）"]
[1,30400430,"缺氧微环境强化的肝癌靶向性自杀基因研究","第一医院","禄韶英","2005-2007",21]
[2,30400515,"重组慢病毒表达TAT-BACE底物肽抑制BACE作用的研究","医学院","董炜疆","2005-2007",21]
[3,30400520,"蛋白酶体在砷剂诱导白血病细胞分化凋亡中的作用机制研究","第一医院","王怀宇","2005-2007",21]
[4,30400387,"TIG基因在角质形成细胞异常增殖中的作用机制","第二医院","郑    焱","2005-2007",22]
[5,30400249,"Pdx1基因修饰大鼠骨髓间充质干细胞定向分化为胰岛样细胞的实验研究","医学院","李冬民","2005-2007",21]
[6,30400174,"细胞骨架机械信号传递系统在衰竭心肌钠通道功能调节中的作用及机制","第一医院","席雨涛","2005-2007",19]
[7,30400131,"感觉神经末梢间兴奋传递参与痛觉外周敏化形成的机理","医学院","曹东元","2005-2007",21]
[8,30470089,"体外培养细胞中HCV的复制、蛋白质组及生物学特性研究","医学院","楚雍烈","2005-2007",20]
[9,30470456,"zg-tPA与eNOS基因修饰/双细胞种植改善小口径人工血管通畅率的实验研究","第二医院","裴    斐","2005-2007",26]
[10,30470633,"迷走神经和乙酰胆碱对心脏不同部位调控的机制研究","医学院","臧伟进","2005-2007",24]
[11,30470915,"安非他明依赖的分子和细胞基础","医学院","李生斌","2005-2007",20]
[12,30471499,"几种真菌毒素对软骨蛋白聚糖代谢及其调控的影响","医学院","曹峻岭","2005-2007",21]
[13,30471532,"丙型肝炎病毒核心蛋白结合蛋白HCBP1生物学功能的研究","第一医院","刘    敏","2005-2007",21]
[14,30471564,"角蛋白17新突变转基因动物模型的研究","第二医院","肖生祥","2005-2007",22]
[15,30471672,"Toll样受体通路信号传导激活门脉高压症脾脏巨噬细胞的机制研究","第二医院","苏清华","2005-2007",21]
[16,30471692,"门静脉高压症脾脏巨噬细胞与正常脾脏巨噬细胞蛋白质表达差异的研究","第二医院","马双余","2005-2007",21]
[17,30471735,"与精索静脉曲张相关的附睾特异基因表达的研究","医学院","张秋养","2005-2007",21]
[18,30471774,"大鼠弥漫性轴索损伤后脑血流和氧代谢的实验研究","第一医院","宋锦宁","2005-2007",21]
[19,30471640,"GPx1-IRES- KLK1转基因小鼠移植肾缺血损伤的保护机制研究","第一医院","薛武军","2005-2007",18]
[20,30471982,"SSd抑制肝肿瘤血管形成及抗肿瘤的分子机制研究","第二医院","程延安","2005-2007",21]
[21,30471826,"FGR的关键期及其影响子代学习记忆的分子机制研究","第一医院","苟文丽","2005-2007",21]
[22,30471827,"新生鼠缺氧缺血脑损伤神经蛋白聚糖表达与轴突再生关系研究","第二医院","李占魁","2005-2007",21]
[23,30470785,"贲门腺癌及其癌前病变的蛋白质组差异分析研究","第二医院","张    军","2005-2007",20]
[24,30470822,"甲状腺内胎儿微嵌合体对自身免疫性甲状腺病发病的影响","第一医院","郭    辉","2005-2007",13]
[25,30471877,"腺伴病毒介导神经营养肽(ADNF-9)治疗感音神经性耳聋的实验研究","第二医院","韦俊荣","2005-2007",21]
[26,30471911,"应力微环境下牙周膜细胞及破骨细胞蛋白表达的质谱分析","口腔医院","周    洪","2005-2007",21]
[27,30471935,"生物光子衰减与死亡时间的相关性研究","医学院","王振原","2005-2007",21]
[28,30470509,"胸部疾病CT诊断后PACS平台的构建研究","第一医院","郭佑民","2005-2007",16]
[29,30471942,"分泌表达NT4-p53N15-Ant融合肽重组慢病毒抗肿瘤研究","第一医院","宋丽萍","2005-2007",21]
[30,30472266,"大黄素、黄芪多糖联合抗乙肝病毒的作用机制研究","第二医院","党双锁","2005-2007",21]
[31,30400101,"血管性痴呆的早期诊断和程度分级的无创伤电生理方法研究","生命学院","徐   进","2005－2005",20]
[32,30471478,"西部农村卫生服务模式研究","公卫学院","高建民","2005－2005",22]
[33,30500204,"用昆虫杆状病毒表达系统表达的钠泵α3亚单位截断性片段治疗高血压","第二医院","张明娟","2006-2008",25]
[34,30500688,"转膜紧密连接蛋白在急性胰腺炎发病中的作用及“清胰注射液”对其干预的研究","第二医院","夏先明","2006-2008",24]
[35,30500438,"角蛋白17基因突变及其表达和雄激素关系的研究","第二医院","冯义国","2006-2008",21]
[36,30500590,"急性单核细胞白血病主动免疫治疗有效后复发的机理研究","第二医院","刘苏虎","2006-2008",25]
[37,30500600,"乳腺癌演进不同阶段组织和血清中核基质蛋白的差异表达及初步分析","第二医院","张淑群","2006-2008",25]
[38,30570775,"急性单核细胞白血病肿瘤新抗原的鉴定及计算机辅助设计多肽疫苗的应用","第二医院","张王刚","2006-2008",22]
[39,30570795,"肺腺癌预警及早期诊断标志蛋白的筛选及其鉴定","第二医院","杨拴盈","2006-2008",25]
[40,30571818,"应用代谢组学方法筛选原发性肝癌侵袭转移标志物","第二医院","李宗芳","2006-2008",28]
[41,30571932,"基因修饰肠神经嵴干细胞移植再建成体肠神经系统","第二医院","高    亚","2006-2008",27]
[42,30571790,"DNA损伤修复与MAPK通路在脑缺血再灌注损伤中的作用机制","第二医院","薛荣亮","2006-2008",27]
[43,30500560,"运用蛋白质组学方法筛选牙周病疫苗候选p.g抗原的反向疫苗学研究","口腔医院","李    昂","2006-2008",25]
[44,30572052,"RNAi抑制aggrecanaes的表达对软骨aggrecan代谢及移植后免疫反应的影响","口腔医院","杨壮群","2006－2008",26]
[45,30572140,"G4PAMAM/VEGFASODN抗乳腺癌血管生成的研究","第一医院","赵新汉","2006-2008",27]
[46,30500119,"基于蛋白组学的胆囊癌FT-IR医学分析模型构建","第一医院","王健生","2006-2008",26]
[47,30500249,"内质网应激在胰岛β细胞脂性凋亡机制中作用的研究","第一医院","崔    巍","2006-2008",27]
[48,30500536,"卵巢癌免疫治疗新策略：在化疗后淋巴细胞减少期行GM-CSF修饰的瘤苗免疫","第一医院","马    军","2006-2008",25]
[49,30500250,"CD40的RNA干扰诱导免疫耐受对Graves病预防的研究","第一医院","吴晓燕","2006-2008",26]
[50,30500502,"诱导/封闭PrLZ表达对前列腺癌细胞生长、侵袭转移影响的体内外实验研究","第一医院","李    磊","2006-2008",25]
[51,30570732,"TRX及其信号调节通路在动脉粥样硬化发生与发展中的作用","第一医院","袁祖贻","2006-2008",26]
[52,30570630,"以JC病毒VLP为载体探讨中枢神经系统定向基因传递","第一医院","屈秋民","2006-2008",28]
[53,30571994,"VEGF/PKC/NO/ICAM-1信号通路在糖尿病性视网膜病变中的作用研究","第一医院","张小玲","2006-2008",26]
[54,30570875,"骨质疏松性骨折的分子遗传学及其风险因子研究","第一医院","王金堂","2006-2008",25]
[55,30571648,"HCV核心蛋白对肝脏干细胞的转分化作用研究","第一医院","马列婷","2006-2008",25]
[56,30571649,"乙肝病毒PreS1蛋白相互作用分子的筛选及其作用机制","第一医院","蔺淑梅","2006-2008",25]
[57,30570733,"尖端扭转型室速发生机制与时空异质性特征的定量心脏电生理研究","第一医院","杨    琳","2006-2008",26]
[58,30571597,"中国农村版Bayley 婴幼儿发展量表的研究","第一医院","刘小红","2006-2008",25]
[59,30571951,"宫颈癌干细胞的分离、鉴定与细胞分子生物学特性的研究","第一医院","郑鹏生","2006-2008",26]
[60,30570631,"三叉神经节离体培养后降钙素基因相关肽表达增高的细胞内信号转导机制研究","第一医院","罗国刚","2006-2008",26]
[61,30571799,"重建胰岛微环境的实验研究","第一医院","冯新顺","2006-2008",27]
[62,60501006,"基于EIS和MRI信息采集技术对乳腺癌生物学边界的测量研究","第一医院","张毅力","2006-2008",23]
[63,30500411,"多巴胺受体在海洛因降低子代学习记忆中的作用机制","医学院","王     莹","2006-2008",23]
[64,30500203,"应用反义p22phox腺病毒载体研究内源性ROS在AngⅡ致心肌细胞肥大效应中的作用","医学院","周     娟","2006-2008",24]
[65,30500575,"大鼠脑缺血后谷氨酸介导的神经细胞再生及其机制研究","医学院","肖新莉","2006-2008",25]
[66,30572347,"大黄ZHE虫丸对血管平滑肌细胞增殖及血管重构影响的分子生物学研究","医学院","刘俊田","2006-2008",25]
[67,30571725,"用NOCIA大鼠模型筛选和鉴定类风湿关节炎的易感基因","医学院","吕社民","2006-2008",28]
[68,30571628,"脂质体松萝酸抗弓形虫的作用及机制研究","医学院","程彦斌","2006-2008",25]
[69,30570976,"血管活性肠肽对脑缺血大鼠血管再生的作用和机制研究","医学院","杨    杰","2006-2008",25]
[70,30570592,"腹外侧眶皮层内GABA能神经元调制阿片与5-HT诱发抗伤害效应的机制","医学院","唐敬师","2006-2008",30]
[71,30572089,"DA受体基因敲除小鼠c-Fos及ΔfosB的表达与调控","医学院","陈    腾","2006-2008",28]
[72,30572184,"血管平滑肌BKCa表达和调控改变在糖尿病血管病变中的作用","医学院","邓秀玲","2006-2008",25]
[73,30570487,"体内可重组复合结构亚微米造影微泡与稀疏微血管及淋巴结超宽带高杂波抑制超声造影","生命学院","万明习","2006-2008",25]
[74,30570494,"兼有超声触发释放与超声示踪特性的载药微系统","生命学院","吴道澄","2006-2008",25]
[75,30570505,"采用双能量X线数字成像技术改进骨密度及骨龄测定的研究","生命学院","张    锋","2006-2008",20]
[null,null,"合计",{"$nulls":3},1753]

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